In April, the mark was seen again, with White House officials revealing it was a sign that Trump was hard at work.
However, people online have become increasingly worried about his health amid a recent image that has circulated X of his hand covered in what appears to be foundation.
The picture show Trump’s hand by his side, with a mismatched pale color covering a large portion of his skin.
People in the comments believe this is a sign of his ill health, and others voiced their worries.
A commenter wrote: “What health conditions could make Trump’s hands look like that?”
Someone else said: “His hands were bruised, his skin pale, his ankles swollen, what is going on with my president?”
Another shared: “Is this real? what happened?”
UNILAD has contacted the White House for a comment.
The White House has previously claimed the marks are a result of shaking hands with numerous people.
Press secretary Karoline Leavitt said: “President Trump is a man of the people and he meets more Americans and shakes their hands on a daily basis than any other president in history.
“His commitment is unwavering and he proves that every single day.”
Leavitt then followed up her point by saying of the president: “President Trump has bruises on his hand because he’s constantly working and shaking hands all day every day.”
After fans pointed out his swollen ankles, the POTUS was diagnosed with chronic venous insufficiency.
The 79-year-old was seen at the FIFA Club World Cup final with visible swelling around his lower legs, leading Leavitt to reveal his diagnosis on July 17.
She read out a message from Trump’s physician, stating: “Importantly, there was no evidence of deep vein thrombosis or arterial disease.”
She went on to explain that he had received different tests to rule out other conditions which came back ‘within the normal limits’.
According to the Cleveland Clinic, chronic venous insufficiency (CVI) happens when the veins in the leg become damaged and no longer work as they should.
Venous disease affects about one in three adults in the US, with one in 20 being affected by CVI.
CVI damages the valves that push blood back up to the heart, leading to blood pooling in the legs.
The pooling can then lead to increased pressure which causes tiny blood vessels to burst, resulting in swelling or ulcers.
Treatment for the condition includes compression therapy, lifestyle changes or even surgery.
The clinic advises to keep the leg elevated for some time every day, ramp up physical activity like walking, and to keep a healthy weight.